Detalhe da pesquisa
1.
New inhibitor targeting Acyl-CoA synthetase 4 reduces breast and prostate tumor growth, therapeutic resistance and steroidogenesis.
Cell Mol Life Sci
; 78(6): 2893-2910, 2021 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-33068124
2.
BRCA1 and BRCA2 mutations and clinical interpretation in 398 ovarian cancer patients: comparison with breast cancer variants in a similar population.
Hum Genomics
; 12(1): 39, 2018 08 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30103829
3.
Tyrosine phosphatase SHP2 regulates the expression of acyl-CoA synthetase ACSL4.
J Lipid Res
; 52(11): 1936-48, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21903867
4.
Study of the Genetic Variants in BRCA1/2 and Non-BRCA Genes in a Population-Based Cohort of 2155 Breast/Ovary Cancer Patients, Including 443 Triple-Negative Breast Cancer Patients, in Argentina.
Cancers (Basel)
; 13(11)2021 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-34072659
5.
Hormonal activation of a kinase cascade localized at the mitochondria is required for StAR protein activity.
Mol Cell Endocrinol
; 300(1-2): 37-42, 2009 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-19007846
6.
Angiotensin II stimulation promotes mitochondrial fusion as a novel mechanism involved in protein kinase compartmentalization and cholesterol transport in human adrenocortical cells.
J Steroid Biochem Mol Biol
; 192: 105413, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31202858
7.
Regulatory mechanisms leading to differential Acyl-CoA synthetase 4 expression in breast cancer cells.
Sci Rep
; 9(1): 10324, 2019 07 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31311992
8.
New enzymes involved in the mechanism of action of epidermal growth factor in a clonal strain of Leydig tumor cells.
Endocrinology
; 149(7): 3743-52, 2008 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-18388199
9.
BRCA1 and BRCA2 Mutations Other Than the Founder Alleles Among Ashkenazi Jewish in the Population of Argentina.
Front Oncol
; 8: 323, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30186769
10.
An arachidonic acid generation/export system involved in the regulation of cholesterol transport in mitochondria of steroidogenic cells.
FEBS Lett
; 581(21): 4023-8, 2007 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-17673208
11.
Tyrosine phosphatases in steroidogenic cells: regulation and function.
Mol Cell Endocrinol
; 265-266: 131-7, 2007 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17207923
12.
Increases in vanilloid TRPV1 receptor protein and CGRP content during endotoxemia in rats.
Eur J Pharmacol
; 566(1-3): 145-52, 2007 Jul 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-17482593
13.
cAMP increases mitochondrial cholesterol transport through the induction of arachidonic acid release inside this organelle in Leydig cells.
FEBS J
; 273(22): 5011-21, 2006 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-17087723
14.
Protein tyrosine phosphatases regulate arachidonic acid release, StAR induction and steroidogenesis acting on a hormone-dependent arachidonic acid-preferring acyl-CoA synthetase.
J Steroid Biochem Mol Biol
; 99(4-5): 197-202, 2006 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-16630718
15.
Role of Protein Phosphorylation and Tyrosine Phosphatases in the Adrenal Regulation of Steroid Synthesis and Mitochondrial Function.
Front Endocrinol (Lausanne)
; 7: 60, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27375556
16.
Silencing the expression of mitochondrial acyl-CoA thioesterase I and acyl-CoA synthetase 4 inhibits hormone-induced steroidogenesis.
FEBS J
; 272(7): 1804-14, 2005 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15794766
17.
An arachidonic acid-preferring acyl-CoA synthetase is a hormone-dependent and obligatory protein in the signal transduction pathway of steroidogenic hormones.
J Mol Endocrinol
; 34(3): 655-66, 2005 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-15956337
18.
The role of mitochondrial fusion and StAR phosphorylation in the regulation of StAR activity and steroidogenesis.
Mol Cell Endocrinol
; 408: 73-9, 2015 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25540920
19.
Acyl-CoA synthetase-4, a new regulator of mTOR and a potential therapeutic target for enhanced estrogen receptor function in receptor-positive and -negative breast cancer.
Oncotarget
; 6(40): 42632-50, 2015 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26536660
20.
The novel desmopressin analogue [V4Q5]dDAVP inhibits angiogenesis, tumour growth and metastases in vasopressin type 2 receptor-expressing breast cancer models.
Int J Oncol
; 46(6): 2335-45, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25846632